LC-MS analysis of intact amino acids using Compact Mass Spectrometer (CMS)

Advion is a mass spectrometer manufacturer based in the United States (since 2021, in France).

The high-performance compact mass spectrometer "Advion expression CMS" provided by Advion is a compact, high-sensitivity single quadrupole MS. Using this CMS and the Intrada Amino Acid column, we were able to rapidly and sensitively analyze 20 different amino acids. Additionally, the amino acids Pro, Tyr, Phe, and Thr were quantitatively detected in the pmol range within 15 minutes.

As a high-sensitivity MS in a benchtop format, the CMS, together with the Intrada Amino Acid column, enables simple and rapid amino acid LC-MS analysis.

• Technical Documentation

  (Courtesy of Dr. Daniel Eikel, Advion, Inc., USA)